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Dogs + Cancer & Tumors

  • Mast cell tumors are most common in the skin of dogs and may appear red, ulcerated, or swollen. They can be itchy and can fluctuate in size. Tumors can range from lower-grade, with minimal spread, to higher-grade, with a high risk of local invasion. Treatment usually involves surgical removal and may require supportive treatment including chemotherapy, radiation therapy, and therapy to target the mutation that instigated the tumor.

  • Melanomas are cancerous growths of the cells responsible for pigmentation of the skin. They can develop anywhere on the body but those on the toes carry the highest chance for malignancy. They may be painful and you may notice your pet licking at the affected area. Surgery is often the treatment of choice and may be followed up with radiation or chemotherapy.

  • Nasal tumors are an uncommon type of cancer but when they do occur, they tend to be malignant and locally aggressive. Staging can be done to determine the type of cancer and if it has affected anywhere else in the body. Treatment can be done in some cases to help relieve clinical signs, most often with radiation therapy.

  • A chemodectoma is a type of tumor made up of chemoreceptor cells. Chemoreceptor cells detect chemical changes in the body and respond by regulating chemical or physical processes. These tumors are most often seen along one of the carotid arteries and the aorta. Brachycephalic breeds are more predisposed to these types of tumors, though they may occur in any dog breed. These tumors are usually locally aggressive, however, there are rare cases of metastasis to other organs, including the lungs, lymph nodes, and bone.

  • Gastrinomas and intestinal carcinoids are neuroendocrine tumors that occur in the pancreas and upper intestine (gastrinomas) and in the intestines (intestinal carcinoids). Generally, neuroendocrine tumors are rare in dogs and cats. This handout outlines their signs, diagnosis, treatment, and prognosis.

  • Medullary thyroid carcinomas and pheochromocytomas are neuroendocrine tumors that occur in the thyroid gland and the adrenal gland, respectively. Generally, neuroendocrine tumors are rare in dogs and cats. This handout outlines their signs, diagnosis, treatment, and prognosis.

  • Small cell lung carcinomas (SCLC) are a rare type of lung cancer. The prognosis for small cell lung carcinoma is generally poor, as it is highly aggressive. This handout outlines their signs, diagnosis, treatment, and prognosis.

  • Odontogenic fibromas, sometimes previously referred to as an epulis, are benign tumors of the mouth often at the front of the upper jaw. These may be locally invasive and may cause some oral pain. Surgery is the recommended course of action to treat this condition.

  • Oral squamous cell carcinomas (SCC) are the most common oral tumor in cats, and second most common in dogs. These tumors are locally aggressive, with a possibility to metastasize. Regardless of the location of SCC, surgery is the typically the standard treatment. Radiation therapy may be recommended following surgery or as a primary treatment for palliative care. Staging is recommended for all cases. If metastasis is present chemotherapy is often pursued.

  • Fibrosarcomas are the third most common oral tumor in dogs and arise from the fibrous and connective tissues of the oral cavity. These tumors are very invasive locally and are often difficult to manage, Diagnosis is based on biopsy. Treatment involving surgery and radiation provide the longest survival times.